Resveratrol is a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi. It is found in the skin of red grapes and is a constituent of red wine. It is currently marketed as one of many anti aging products.
It is still being researched and explored but scientists are very optimistic about the health properties associated with this unique nutrient.
The first know source of resveratrol was Japanese Knotweed. The Japanese understood it’s ability too balance the body hormones and also counteracts the oxidization of melanin cells, the condition which initiates aging spots and also triggers collagen production.
Resveratrol has been found to induce cell cycle arrest when added to cancer cells grown in culture also it has been found to inhibit proliferation and induce apoptosis in a number of cancer cell lines by interfering with all three stages of carcinogenesis ” initiation, promotion and progression.
For cancers, the evidence is uncertain, even if massive doses of resveratrol are used. However in vitro resveratrol interacts with multiple molecular targets and has positive effects on the cells of breast, skin, gastric, colon, esophageal, prostate, pancreatic cancer, and leukemia.
Although not yet tested in humans, resveratrol was reported effective against neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington’s disease and Alzheimer’s disease.
Researchers at the Weill Medical College of Cornell University reported that dietary supplementation with resveratrol significantly reduced plaque formation in animal brains, a component of Alzheimer and other Neurodegenerative diseases. In humans it is theorized that oral doses of resveratrol may reduce beta amyloid plaque associated with aging changes in the brain.
Aggregation of platelets is one of the first steps in the formation of a blood clot that can block a coronary or cerebral artery, resulting in a stroke. Resveratrol has been found to inhibit platelet aggregation in vitro.
Studies of numerous species have shown that a reduction in calories has been linked to a longer lifespan. Resveratrol appear to mimic several of the biochemical effects of calorie restriction. There is evidence that resveratrol may be a calorie restriction mimetic, which may be helpful in promoting a longer lifespan.
Recently a report stated that resveratrol extended the lifespan of mice on a high-calorie diet such that their lifespan was similar to that of mice fed a standard diet.
Resveratrol effectively scavenges (neutralizes) free radicals and other oxidants i a test tube.
A recent 60 minutes episode highlighted the work of Dr. Christoph Westphal and Harvard biochemist David Sinclair, whose research suggests that resveratrol can delay the aging process and prevent many gerontological diseases. It is also claimed that this antioxidant can boost stamina, reduce lung inflammation stemming from chronic pulmonary disease, and help stave off cancer.
In detail this natural substance is being trialed against,
Free Radicals & Dangerous Toxins, Carcinogens of all types, Heart Disease, Stroke Risk, Cellular Level dysfunction, Brain and cell degeneration, and Lactic Acid Buildup.
And Promoting ,
Good Cholesterol, Natural Energy and Metabolic Rate.
As a food supplement resveratrol can be take orally, with a recommended dose of two capsules per day depending on the manufacturer.
Note: It is important to keep in mind that many of the biological activities discussed above were observed in cells cultured in the presence of resveratrol at higher concentrations than those likely to be achieved in humans consuming resveratrol orally.
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